#melanocortins
3 pieces tagged melanocortins.
Where the line isBremelanotide, Vyleesi and the intranasal program that was never approvedOne FDA-approved application, one route, and no intranasal bremelanotide product ever approved. The dates, the FDA review language that closed the nasal program, and where PT-141 sits in 2026.
The moleculesMelanotan II, PT-141 and afamelanotide: one parent, three analoguesAfamelanotide, Melanotan II and bremelanotide all descend from the 13-residue hormone alpha-MSH. Two became approved drugs; Melanotan II never did. Structures, lineage, FDA's own words on MT-II, and status as of September 2026.
The moleculesHow to read a peptide sequenceThe one- and three-letter codes, which end is which, what Ac- and -NH2 mean, how D-residues, rings and lipids are written, and four worked examples from the catalog.
Nothing here is medical advice. Everything on this site is supplied for laboratory research use only.