#handling
5 pieces tagged handling.
- HandlingWhy some peptides dissolve badly: charge, hydrophobicity and gellingNet charge, isoelectric point, hydrophobic residue content and beta-sheet self-assembly decide whether a peptide dissolves clear, turns cloudy or gels. The chemistry, with worked examples from published sequences.
- HandlingWhere the 28 days number comes from (it is not peptide data)The 28-day figure often attached to peptides is a pharmacy standard for preserved multi-entry containers, tied to a 28-day microbiology test. It measures preservative performance, not what happens to a peptide in solution.
- HandlingTFA salt or acetate salt: what the counter-ion changes about the vialWhere trifluoroacetate comes from, why it stays bound to basic residues, how much of a vial's mass it can be, what the literature reports about it in cell work, and what a certificate should say about salt form.
- HandlingDo lyophilized peptides survive heat in transit?Why a dry solid is more stable than a solution, what ICH-style testing at 25 °C and 40 °C has shown for lyophilized peptides, what changes first, and why a warm parcel is a different question for a powder than for a liquid.
- HandlingFreeze-thaw, aliquots and the residues that oxidizeWhich amino acids oxidize, deamidate or hydrolyse, what freezing and thawing do to a solution physically, what manufacturers' guides say about repeated freezing, and where those residues sit in the sequences we stock.
Nothing here is medical advice. Everything on this site is supplied for laboratory research use only.